ASD - ALTERNATIVE SPLICING


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FIELD NAME
FIELD VALUE
  
AEdbMotif ID:94
Internal ref. ID:
Submitter name:MAREK, STEFAN
Entry date:21-SEP-2004 10:10:13
Modification date:19-SEP-2005 15:50:45
 
Regulatory sequence name:beta-globin exon 2
Entry type:Exon enhancer
Sequence origin:Exonic
Organism:Homo sapiens, human
Binding factors:ASF/SF2
 
EMBL/Genbank/DDBJ/RefSeq Accession number:
Ensembl ID:
AEdb ID:
Sequence:GGACAA
Mutated regulatory sequence:
 
Methods:Unknown
Keywords:
 
Citation line:Schaal, T. D. and T. Maniatis. 1999. Multiple distinct splicing enhancers in the protein-coding sequences of a constitutively spliced pre-mRNA. Mol.Cell Biol. 19:261-273
PubMed ID:9858550
 
Comments:The sequence GGACAA in region F of exon 2 is likely to be part of an SF2/ASF-dependent splicing enhancer, but furthermore this sequence was not experimentally shown. The beta-globin sequence was shown to have enhancer activity in a heterologous context (dsx) but not in the natural one.
(activated in workbench):Y
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