ASD - ALTERNATIVE SPLICING


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FIELD NAME
FIELD VALUE
  
AEdbMotif ID:80
Internal ref. ID:
Submitter name:MAREK, STEFAN
Entry date:20-SEP-2004 14:05:19
Modification date:19-SEP-2005 17:47:39
 
Regulatory sequence name:c/cgrp exon 3
Entry type:Exon enhancer
Sequence origin:Exonic
Organism:Rattus sp., rat
Binding factors:SRp40, 37-kDa protein
 
EMBL/Genbank/DDBJ/RefSeq Accession number:
Ensembl ID:
AEdb ID:
Sequence:GAAGAAGAAG
Mutated regulatory sequence:
 
Methods:Unknown
Keywords:
 
Citation line:Yeakley, J. M., J.-P. Morfin, M. G. Rosenfeld, and X.-D. Fu. 1996. A complex of nuclear proteins mediates SR protein binding to a purine-rich splicing enhancer. Proc.Natl.Acad.Sci.USA 93:7582-7587.
PubMed ID:8755518
 
Comments:The motif from exon 3 was inserted into exon 4 and the switch to calcitonin mRNA was observed. The motif was not shown to be functional in the natural context,despite this is likely to be the case.
(activated in workbench):Y
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