ASD - ALTERNATIVE SPLICING


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FIELD NAME
FIELD VALUE
  
AEdbMotif ID:217
Internal ref. ID:
Submitter name:DARYA, STEFAN
Entry date:27-SEP-2004 19:22:03
 
Regulatory sequence name:transformer, exon 2
Entry type:Intron silencer
Sequence origin:Intronic
Organism:Drosophila melanogaster, fruit fly
Binding factors:Sxl, U2 snRNP
 
EMBL/Genbank/DDBJ/RefSeq Accession number:
Ensembl ID:
AEdb ID:
Sequence:TTTTTTTT
Mutated regulatory sequence:
 
Methods:Unknown
Keywords:
 
Citation line:Valcárcel, J, Singh, R, Zamore, P and Green, M: The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA. Nature 1993, 362:171-175.Inoue, K, Hoshijima, K, Sakamoto, H and Shimura, Y: Binding of the Drosophila Sex-lethal gene product to the alternative splice site of transformer primary transcript. Nature 1990, 344:461-463.
PubMed ID:7680770 , 1690860
 
Comments:Location of element-upstream of non-sex-specific 3' splice site (-4 to -11)
(activated in workbench):Y
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